Reishi Mushroom (Ganoderma lucidum)

Reishi mushroom (Ganoderma lucidum), also known as Lingzhi in China, is a well-known herbal remedy in Asia. Some of the benefits attributed to reishi mushroom are related to the liver, nervous system, stress, and the immune system.




Li, Fenglin, Yiming Zhang, and Zhijian Zhong. Antihyperglycemic Effect of Ganoderma Lucidum Polysaccharides on Streptozotocin-Induced Diabetic Mice. Int J Mol Sci. 2011; 12(9): 6135–6145.

Chan, Wing Keung, et al. Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function. J Hematol Oncol. 2008; 1: 9.

Jan, Rong-Hwa, et al. Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen. BMC Immunol. 2011; 12: 31.

Dai, Shuyan, corresponding author Jingjing Liu, Xiaofei Sun, and Ning Wang. Ganoderma lucidum inhibits proliferation of human ovarian cancer cells by suppressing VEGF expression and up-regulating the expression of connexin 43. BMC Complement Altern Med. 2014; 14: 434.





Lin, Wen-Chuan, and Wei-Lii Lin. Ameliorative effect of Ganodermalucidum on carbon tetrachloride-induced liver fibrosis in rats. World J Gastroenterol 2006 January 14; 12(2):265-270.

Cheng, Kun-Chieh, et al. Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction. BMC Genomics 2007, 8:411; doi:10.1186/1471-2164-8-411.

Liang, Chan-Jung, et al. Ganoderma lucidum Polysaccharides Reduce Lipopolysaccharide-Induced Interleukin-1β Expression in Cultured Smooth Muscle Cells and in Thoracic Aortas in Mice. Evid Based Complement Alternat Med. 2014; 2014: 305149.

Hsu, Jia-Wei, et al. Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation. Evid Based Complement Alternat Med. 2011; 2011: 358717.

Pan, Deng, et al. Antidiabetic, Antihyperlipidemic and Antioxidant Activities of a Novel Proteoglycan from Ganoderma Lucidum Fruiting Bodies on db/db Mice and the Possible Mechanism. PLoS One. 2013; 8(7): e68332.